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| Trends by Drug Type | Trends by Relative Popularity |
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| Trends in Past Year Substance Use Among Those 12 and Older (1979 - 2008) | |||||||||||
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| Year | Population | Alcohol | Cigarettes | Marijuana | Pills | Cocaine | Hallucinogens | Inhalants | Meth | Crack | Heroin |
| 1979 | 180,343,000 | 131,443,000 | -- | 29,869,000 | -- | 8,608,000 | 5,260,000 | -- | -- | -- | 427,000 |
| 1982 | 186,440,000 | 126,534,000 | -- | 29,685,000 | -- | 10,458,000 | 4,149,000 | -- | -- | -- | 323,000 |
| 1985 | 192,605,000 | 140,394,000 | 78,026,000 | 26,145,000 | 11,988,000 | 9,839,000 | 3,198,000 | 2,657,000 | -- | -- | 347,000 |
| 1988 | 198,347,000 | 135,044,000 | 76,446,000 | 19,492,000 | 9,151,000 | 7,151,000 | 3,200,000 | 2,441,000 | -- | 1,459,000 | 508,000 |
| 1991 | 202,859,000 | 138,113,000 | 73,419,000 | 18,067,000 | 7,314,000 | 5,284,000 | 2,562,000 | 2,379,000 | -- | 1,451,000 | 359,000 |
| 1992 | 205,713,000 | 133,090,000 | 72,409,000 | 16,322,000 | 6,260,000 | 4,332,000 | 2,530,000 | 1,889,000 | -- | 1,144,000 | 304,000 |
| 1993 | 207,199,000 | 137,771,000 | 68,831,000 | 17,510,000 | 6,336,000 | 3,947,000 | 2,479,000 | 1,940,000 | -- | 1,416,000 | 230,000 |
| 1994 | 209,411,000 | 140,121,000 | 66,475,000 | 17,813,000 | 6,056,000 | 3,664,000 | 2,725,000 | 2,213,000 | -- | 1,258,000 | 281,000 |
| 1995 | 211,532,000 | 138,314,000 | 67,639,000 | 17,755,000 | 6,166,000 | 3,664,000 | 3,416,000 | 2,308,000 | -- | 1,018,000 | 428,000 |
| 1996 | 214,047,000 | 138,912,000 | 69,098,000 | 18,398,000 | 6,652,000 | 4,033,000 | 3,602,000 | 2,427,000 | -- | 1,375,000 | 455,000 |
| 1997 | 216,206,000 | 138,500,000 | 70,709,000 | 19,446,000 | 6,112,000 | 4,169,000 | 4,063,000 | 2,329,000 | -- | 1,375,000 | 597,000 |
| 1998 | 218,445,000 | 139,807,000 | 66,735,000 | 18,710,000 | 5,759,000 | 3,811,000 | 3,565,000 | 2,009,000 | -- | 971,000 | 253,000 |
| 1999 | 221,123,000 | 137,741,000 | 66,636,000 | 19,102,000 | 9,220,000 | 3,742,000 | 3,191,000 | 1,937,000 | 1,140,000 | 1,045,000 | 353,000 |
| 2000 | 223,280,000 | 138,179,000 | 65,009,000 | 18,589,000 | 8,761,000 | 3,328,000 | 3,483,000 | 1,918,000 | 1,031,000 | 721,000 | 308,000 |
| 2001 | 225,636,000 | 143,638,000 | 65,577,000 | 21,086,000 | 11,102,000 | 4,186,000 | 4,597,000 | 1,922,000 | 1,341,000 | 1,027,000 | 456,000 |
| 2002 | 235,143,000 | 155,476,000 | 71,310,000 | 25,755,000 | 14,795,000 | 5,902,000 | 4,749,000 | 2,084,000 | 1,755,000 | 1,554,000 | 404,000 |
| 2003 | 237,682,000 | 154,540,000 | 69,853,000 | 25,231,000 | 15,163,000 | 5,908,000 | 3,936,000 | 2,075,000 | 1,602,000 | 1,406,000 | 314,000 |
| 2004 | 240,515,000 | 156,686,000 | 69,909,000 | 25,451,000 | 14,849,000 | 5,658,000 | 3,878,000 | 2,255,000 | 1,808,000 | 1,304,000 | 398,000 |
| 2005 | 243,220,000 | 161,626,000 | 70,832,000 | 25,375,000 | 15,346,000 | 5,523,000 | 3,809,000 | 2,187,000 | 1,603,000 | 1,381,000 | 379,000 |
| 2006 | 246,022,000 | 162,415,000 | 71,676,000 | 25,378,000 | 16,482,000 | 6,069,000 | 3,956,000 | 2,218,000 | 1,889,000 | 1,479,000 | 560,000 |
| 2007 | 247,845,000 | 162,876,000 | 70,569,000 | 25,085,000 | 16,280,000 | 5,738,000 | 3,762,000 | 2,080,000 | 1,343,000 | 1,451,000 | 366,000 |
| 2008 | 249,815,000 | 165,071,000 | 69,991,000 | 25,768,000 | 15,166,000 | 5,255,000 | 3,678,000 | 2,047,000 | 850,000 | 1,109,000 | 453,000 |
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